Dave what kind of 1911 is it as others may be able to give more insight on a type or brand specific problem.
Make sure when you make changes as said above change one thing at a time so you know what resolved it.
Also if first shooting session straight from box i would get a few jacketed bullets (atleast a box of 50) and just shoot them to help smooth barrel inconsistencies out. Then I would start all over with the lead and lube you tried originally.