I suggest 25 gr of 1680 has a chance of not making much past the end of barrel (7,000psi/900fps)
Take a look at Alexander Arms own 1680 data for "400 grain-ish" bullet
http://www.alexanderarms.com/images/..._reloading.pdf
also... Google < Accurate 1680 Beowulf > and look for consistent reports -- even if "from the Internet"