FWIW my Bush Cary right now is 200gr Lyman 358430 RN over 6 gr of Unique. Over my Chrony avg vel. of 10 rds is 1,031 fps five yards from the muzzle. Test done muzzle up. Standard deviation was 8, Ext. Spread 48 out of my 4.2" Ruger GP-100.
Both my Ruger GP100 and 686 No Dash are very accurate out to 20 yards. Beyond that the variable would be me not the cartridge or gun.
We don't CCW up here and Wildernous Carry is not widely held but it occurs to me IF I lived in an urban setting and actually felt I needed to be armed, a 9MM polymer pistol 4" or less would be my first choice. Those little .380's are nice but their bark ie recoil was far greater than their bite. Surely a Glock 19 or the S&W M&P Compact both in 9MM would now be better options than a short barreled revolver. Time moves on.
Take Care
Bob
ps I know our situations are completely different and the above is not meant to be critical. Your options for self defense using handguns has changed since the 1960's