Red Dot and 4198 are too far of extremes for 45LC. RedDot is too fast and 4198 too slow.
For a heavy 45LC load you need something like Herco, Blue Dot, 2400, 4227, maybe even Unique.
I have used 9.0gr Unique, and 15gr 2400, both are stiff loads in 45LC.
Blue Dot, 2400, is the way to go for heavy 45LC loads.