Which is better for big game hunting and wilderness protection from large animals, such as boars or bears: .45 caliber, 300-to-350 gr. boolits traveling between 1300 and 1500 f.p.s. or .475-to-.500 caliber, 400-to-450 gr. boolits traveling around 1000 f.p.s.? I've never seen this question addressed in any forum or by any gun writer. For me, shooting the big Linebaugh calibers, with heavy boolits, at over 4 football fields per second velocity ---the obvious solution --- is out of the question. I'm almost 64, have pain-free wrists and I need to keep them that way. Also, I honestly can't afford to have several different caliber pistols built by such masters as Bowen, Stroh or Linebaugh. This may be my one and only custom hunting handgun and I want to get it in the right chambering. Thank you kindly, in advance, for your assistance in this matter.