I have some 45acp brass that has a larger flash hole than others. I believe they are Winchester. Has anyone noticed a difference in pressures or anything detrimental if small or large hole brass were loaded the same with primer, powder or bullet. I no longer have a 45, but I gave most of my brass to my brother because a friend of his recently purchased one. I did not give him the large hole brass mainly because I wasn't sure if the larger hole brass need to loaded different.