Logically, a single flute (relatively large) fluted nose system could be operated by simply opening and closing the mold.
Resulting water dropped (relatively hard tough WW slugs) could be powder coated and put through a LEE push through sizer nose first to readily yield finished sized slugs ready to put into a case.
Simplifying the thought a bit, a huge single large flute could be designed to align with the mold parting line such that you got maximum tissue displacement effect by a huge flute area and a reduced "as cast" weight for faster bullet travel.
The cast lead slug would be forced out of shape during impact, but would still perform better than most hollow point lead slugs resulting in large tissue damage and relatively deep penetration.
This is a thought for discussion, or if such a mold exists we could ring in the mold maker for the practical aspects of what he can do with the idea.